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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '217ebaff46ac97fc70d02674cf441b2dc7d800cd4ad2bc5c7333937afe991a56' 
  AND token = 'aeGVRZi20kM5VKTE8WKSwnEYC6/D85JUOfq7U/Bp9bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}