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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfc2270c6d3a01f8208ce542dfe3f4c57ed914a46ea0c8c787f2027084f65a92' 
  AND token = 'GdZoONn0fK+sY0Eb6BRTb7Py72o0nfdJgcW6eTqz0UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}