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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8343bd8189545cccd2fe35e472cc74f4e53c9903e20f93f488fd98c15f83944' 
  AND token = '6lwh5pWt2N0BtZsB5ZOVq11A+48aQVdE80lpIoeLFo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}