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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aa2a78cc8fce25d8a03e9043a4cbf100fd8dc4930b16aa476413fe203d53cb2' 
  AND token = 'JPCg1IRVkhSQd4e8iJ26k6TfDqqN9tP5Aw9l9M3qagI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00291

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}