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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2266dfcea856c008b330da9024c6f856d3fb27a2d3cadbef32ddea3ad5aa885' 
  AND token = 'NnmGJO5vF4gxe2ztVyoUc91/MeCaT5ePBoIrEukOlqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}