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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5aa27d058517ea85de9c38eed949f9f418f01083439dd1cf25b8aee8da1be70' 
  AND token = 'ODCe+x3zyoawWnMVEjAjXZnVmHj2Lk1/1qHhcJZzhsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}