SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f257d5234a8915d3a665fb0644509ffdb9d641be0cc141ca3af47402acb508' 
  AND token = 'ZAAu0HyysHxuVP4/j9Carg01maEEPC+aVuz0ENdg/L4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}