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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9431db713ee78df4b23d7312e5a9dc39f9f44b16cf47c05ebfe3af3cba189610' 
  AND token = '+nfVPm/ud3XGMfRANTS2oVZr4pnlIziMN74AiHMlitk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}