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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9cebc800c57e3446324c7943f51ede1da891c3c10d271a89980be1a33973c3' 
  AND token = 'F+YOD5fqgabDGKrh06F0sTc+9BfVUhWhhaM1iu20ai4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}