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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f3e6656be44037d4a3079d875f96804313609fb308bb34960760b81a044dbfa' 
  AND token = 'OY1OsnoMY6M6djhYD6zg4/C1M37SgZrfWYOcQXbzdys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}