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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c1305c5bf0bdcd1a81c056991184839e69dbd57cb11b935a8620e64026068c' 
  AND token = 'OhZQKrMVtzYSV9dPFBSk5P1iCfH6qJ+iJ1IP5vX6nXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}