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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c6278e01486f75271e85357b271c0f283ce4570ada7897297a2a99d801be53e' 
  AND token = 'R5m7WXnODYZ9BB3UMnOMa3MUkn0lMWZw6Pik8+Ap0gU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}