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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea743bfec59199509d0911b2e1ce650809719a5a87a4a6555f6e35af7f8050d' 
  AND token = '2uzssDzb9kB1LHRu8En6brn1hp+stY+IRjRFtij0IPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}