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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dcd44d70860fcbb54d19a3a78e73388da1d6331db1a0cba8d5fdcaf7b01b7c2' 
  AND token = '5NXbECiwKqV5lcEuyie47XVPYaK2k/Bsma3AayM5L/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}