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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40eb5671f1e26a6ec8bdfd99fba7d5433b644674ac3ba935ece6e93268ed080e' 
  AND token = 'u51/MC2WVSwbUZCiIgkZQkjfSNZ/sao1C/d6UIU2jNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}