SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0776707a7de87741bf4a6505d2e054b91e4d2671aaec869c324b9c16807d53c6' 
  AND token = 'CawL3NNWlJ3/Ftzmihxq9zAIy0WqBSV3cOKadXnuF64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}