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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ca10dc0fd37f0bd75e53c7d6ed9e605499a45903d0b514869d2277dd587c82' 
  AND token = 'Iz9dDRrPsorNG4U/lypYLZGt4qtCnrDNXW4vo1/rASo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00177

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}