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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '271ad1761b6b8f61d1295603ac5ae28cd37c2736dbb8f0e96f67b07ff6f6c361' 
  AND token = 'jWHpydmxywp+HmSV5wYn2a4DVeHnzfQiVijBJyO0AEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}