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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dc12b58e5b90a42fd752bf820352435f8210b5f8a1d8510c754fcb027802a4d' 
  AND token = 'nWJnf1J47xRCFhUKOQS31NPWhhLsnGzVEQR8OU8vDXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}