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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0def902f6627ee1285934cc1f03f8ddea57b584cff37578cdec7902dee18f1d1' 
  AND token = 'J2oa39mOFs44nx5RdM3dUyEmHVpBbBQhBrF7Ej5uTQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}