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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4296e4249f1f7753f1502cc7e0c97ec5a3df9e3e260c4b1d0e295630bed90201' 
  AND token = '9/rHnLXt8qNAc/xtqO8GF2ucKYOhwQ3Z/ChX0UnNuoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}