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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '852e62acff7a5b5e5b5d6c3cb48e417d983c7ff6b5c81c976747adee8f4d254f' 
  AND token = '+aauWfMA8j9mHewu2wPvZmZFqoL1QHahSeKwBMaq4BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}