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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7caa12728b1e1d098a3d7a074dcfb055483412b13a7b064902edd6f6f7736e8f' 
  AND token = 'CnFm4vcRoCYRhI82R8SZb3SmxpuDr/NkA7pkjQjiHe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}