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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4befe3ac059e31e0d313a91f384fe6eab6fb2007d6805936ef3619b5421804e1' 
  AND token = 'wmT8ynNwVI0vjM0EvnveS5Z9cIa6nVgM+A64BV0e0Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}