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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a01e65be5e8e25aaac1f20c03ffc915452c6a3ae4d4fde720313c27ea45aca33' 
  AND token = 'r5bF/sdeC7oTlCbA//L4BAsUXEUbiIVcUBy5krUcUGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}