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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9ead4767a719f151e627d71c46f20f63544b1e81ca070516c0a6cf85a0bc89' 
  AND token = '5H2JlLVtpD7Dm6CQ0uv7c2qlKYLeIS2OilVWzJIU1vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}