SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e875c801b46a01b4426ddea19bf57101c973fc4b29e962d3a6e488db8c73307' 
  AND token = '/zs1rQPeF6lb12neNQCFsUvOMO1t74UOpeozDrxQolk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}