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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '586b5c036ad1b0dd2228a4d19ad57af38e01db25200a0a0519a4d314222e9907' 
  AND token = 'H5RF1HYx7T3zUCqmT4A4HfnBkSV/2rnjsEnnU8YUbCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}