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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4127f187b88a931723697f85984414a0788dc29c1a035cc97fe1610b54b64039' 
  AND token = 'JOzU5zwSDTp6N1L+O86qHoXvzCL1kPpzX02g0mIbH2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}