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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bf976f010a702a1a7956aa1ba48ccd9110ddcd97635324d1f3a1d93c3feb4b8' 
  AND token = 'CtP1QkPtktwhdyihM9OFLG8yuiQ1Bvss+ZPhoQhhCFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}