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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0af9f30e50bbfdca047e6e87a1b48eb5f2a804f2e4d189515ff794d6758581b' 
  AND token = 'iF4OmKuSeBWV19WmLuVHvh3EPzozZtWyYvHrnhhXp0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}