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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '050db5b4975045e99ee65cdde41599558cb0027d6c99c5f607f983343245a2a2' 
  AND token = 'CoF+2LxXPQ44uzBiB9pI4s/PZ9qm6L/r+EmIhYTj+tM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}