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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f0e33ac803aefc4b4afaaa851ac5474904e029b9aac8896068f97fef97baf63' 
  AND token = '8V3PDvCh3CPbdTP9Mw4dDeLwkuv0QQRYyJc3ei8EBjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}