SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e7ab9c578a83f833316c365081a886470f4bf0a23bc8ded1ef5c37d14d6df6b' 
  AND token = 'SUgS+tuGnkE1Nq7jrR0c5f+NCCL1K+ElFrL8heWOLQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}