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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7854f5cc64371cc669d9599992a030c03865f2d1c51d3ee186a990d7350717d' 
  AND token = 'J4dFyA5Tc+rz8AisiZw7irVz0WXk3f+mdFSjfY4X4/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}