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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d0adabf92156d1b52593c16e5c2999793434e59aa5dfd2dd651d7a3a7220e04' 
  AND token = 'dLegPC0XRiNFwsF+8JLBxc2hsB8frG+1jHppFeB1hZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}