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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac493e3412ce880b45afb9f69af39037e0644177b5a06f9cc68eee0a65e6d86' 
  AND token = 'eLzDqUPGc5I7EdftFTVi5iMdN0bE7aUpLXD6nlBnTWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}