SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34676187f2affc003872e9cad6d30ba8c23a2e52901d72a4f06680e47c045ae3' 
  AND token = 'EH1OS9XCBUts6RRfZuf11l/sNx/7VDHgB5gAW5A7v50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}