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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294e19f00ecc4a963e983e4d81b2c62f21b6454df387cefa5ba82b167863575f' 
  AND token = 'sMsM5I/SWM9gQbwcqlF14uS0M7sF7iM4hyrH7wEkcqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}