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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b1ce6d5178b7853c94cf3ea6fd72499739b4604ab8f3808cfc795eadaa90010' 
  AND token = 'Hwq7O/6T1hPb5gv+beMFz639RPsHHzXQ7kF/7Nj7BMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00224

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}