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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48617260676eda4f6bbd8b4c712013647babb3457a1d08347325b4997c6b40a0' 
  AND token = 'PS4vxFXkyfSfyV4V2uS+ad9mhhAepM5O0u4wgYAPJ6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}