SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2e9db683bff78990b63798955a4b86a8c1716975fd76f3f6cdc48af8c84ab19' 
  AND token = 'JRUIPgyRRUIyLsOM/4/rBsfO8byKcV9vuaJ885u7eHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}