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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '590009b5ac0437d01aa95d80f76ab78743d46319065bea3be3d6b0d7bb45c934' 
  AND token = 'U88dlKhVHbpuiYC7zt+pHBkKZ1L7BTvoi9FdRxbVWzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}