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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a943c05ebd723f82866518053b414cc4587d227e30da3478e3fa0b3147b365b8' 
  AND token = 'Rnb5vFSy9EBecCiJ8QCkl6BQko8vG2JwTTXgUqzdQSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}