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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ee8cb59d0f4270d768077ca682bb3e5075c6ea836abedeb7edaaf9e1061cdf' 
  AND token = 'HPuAtM/3FpknZmydmRxwqKGfCYo/fp99L20eL9LS+PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}