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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d53fc22d8eb998e4399c1bbb6c07731f9d1b58dd5c8156e8626c78b753cb9f6' 
  AND token = 'yn4R51JAJH4DIF6OSPNo/90bm9ooe9belvLNN31asZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}