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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d017f036a41cfeafbdf7ec2b60b822a6009585f43dd0ef451929e77ed8d9fb5' 
  AND token = 'qsnvPVbAjvS0f2WrwVfETD4AEwlS3zgA1866bVEvXQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}