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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601bf13a2e24e374df8238d94caf8c64827ae407738fe707ef1cd79b6b4b99ca' 
  AND token = 'myUO0g+U26ody26QGyPS+nrB5pXgD6aCoBHG+DXoigY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}