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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'defa398682bb0140271f26b7d3c6cc215bb6069c91dc4ba261a622a744c467f6' 
  AND token = 'rXLxw+sGYQTP6eUlPsfTS5O0OC7dXMeYiXUy1XLs05c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}