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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd57c31f65de74fc0781a0a861c8dd3bccaface42d9e5bc3483f7bf13841214' 
  AND token = 'ICH6lpMNMemsf8WvzTx0ew4+Vbh3dTjl4TDcUd34xs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}